'Microarray data analysis: How to get from raw data to significant biological information'

A live webinar presented December 11, 2007 by Peter Roberts, Ph.D.

Utilizing data generated using Illumina human Beadarrays (ArrayExpress: E-TABM-116) and Affymetrix rat whole genome GeneChips (GEO: GSE5350) as examples, the process of microarray data analysis from beginning to end will be described. The emphasis will be on workflows for analyzing paired microarray data, using the Illumina statin study as an example, and multiple sample groups with ANOVA and two-way ANOVA, using Affymetrix data from the MAQC rat toxicology study as the exmple. This statistical analysis identifies significantly differentially expressed genes. The significant biological functions associated with those genes will be identified from gene ontology and pathway analysis.

The GeneSifter Data Center is an online resource providing access to diverse sets of microarray data, supplemented with side-by-side tutorials. The site already contains a number of data sets from previous webinars focused on other fields of study. It is free for examination and use, and requires only brief registration at www.genesifter.com/dc.